Please ensure Javascript is enabled for purposes of website accessibility
More Deaths, No Benefit From Malaria Drug in VA Virus Study
gvw_ap_news
By Associated Press
Published 5 years ago on
April 21, 2020

Share

A malaria drug widely touted by President Donald Trump for treating the new coronavirus showed no benefit in a large analysis of its use in U.S. veterans hospitals. There were more deaths among those given hydroxychloroquine versus standard care, researchers reported.

About 28% who were given hydroxychloroquine plus usual care died, versus 11% of those getting routine care alone. About 22% of those getting the drug plus azithromycin died too, but the difference between that group and usual care was not considered large enough to rule out other factors that could have affected survival.

The nationwide study was not a rigorous experiment. But with 368 patients, it’s the largest look so far of hydroxychloroquine with or without the antibiotic azithromycin for COVID-19, which has killed more than 171,000 people as of Tuesday.

The study was posted on an online site for researchers and has has not been reviewed by other scientists. Grants from the National Institutes of Health and the University of Virginia paid for the work.

Researchers analyzed medical records of 368 male veterans hospitalized with confirmed coronavirus infection at Veterans Health Administration medical centers who died or were discharged by April 11.

About 28% who were given hydroxychloroquine plus usual care died, versus 11% of those getting routine care alone. About 22% of those getting the drug plus azithromycin died too, but the difference between that group and usual care was not considered large enough to rule out other factors that could have affected survival.

[covid-19-tracker]

Researchers Did Not Track Side Effects

Hydroxychloroquine made no difference in the need for a breathing machine, either.

Researchers did not track side effects, but noted a hint that hydroxychloroquine might have damaged other organs. The drug has long been known to have potentially serious side effects, including altering the heartbeat in a way that could lead to sudden death.

Earlier this month, scientists in Brazil stopped part of a study testing chloroquine, an older drug similar to hydroxychloroquine, after heart rhythm problems developed in one-quarter of people given the higher of two doses being tested.

Many doctors have been leery of the drug.

At the University of Wisconsin, Madison, “I think we’re all rather underwhelmed” at what’s been seen among the few patients there who’ve tried it, said Dr. Nasia Safdar, medical director of infection control and prevention.

Patients asked about it soon after Trump started promoting its use, “but now I think that people have realized we don’t know if it works or not” and needs more study, said Safdar, who had no role in the VA analysis.

The NIH and others have more rigorous tests underway.

DON'T MISS

Trump Says Musk, Vivek Will Form Outside Group to Advise White House on Government Efficiency

DON'T MISS

Fate of Clovis Trustee Race Still Up in the Air. So Are Clovis, Sanger School Bond Measures.

DON'T MISS

Richardson Widens Lead Over Bonakdar in Nail-Biting Race for Fresno City Council

DON'T MISS

What to Know About John Ratcliffe, Trump’s Pick for CIA Director

DON'T MISS

Here Are the People Trump Has Picked for Key Positions So Far

DON'T MISS

Waymo’s Robotaxis Now Open to Anyone Who Wants a Driverless Ride in Los Angeles

DON'T MISS

Fresno County Man Accused of Filing Fake Disability Claims in $300K Fraud Scheme

DON'T MISS

Trump Nominates Fox News Host Pete Hegseth for Defense Secretary

DON'T MISS

Economists Warn of Inflation and Debt Risks in Trump’s Second Term Plans

DON'T MISS

How Many Smoke Shops Is Too Many? Fresno Plan Would Allow Only 49

UP NEXT

Chris Wallace Is Leaving CNN, Eager to Explore New Media Landscape

UP NEXT

US Regulators Investigating Whether Engines on 1.4 Million Hondas Might Fail

UP NEXT

When to Catch the Last Supermoon of the Year

UP NEXT

Mattel Says It ‘Deeply’ Regrets Misprint on ‘Wicked’ Dolls Packaging That Links to Porn Site

UP NEXT

Trump to Target Iran’s Oil Trade in Renewed ‘Maximum Pressure’ Campaign

UP NEXT

4B Movement: After the Election, a Call for Women to Swear Off Men

UP NEXT

FBI Thwarts Iranian Murder-for-Hire Plan Targeting Donald Trump

UP NEXT

Wave of Racist Texts After Election Prompts FBI Scrutiny

UP NEXT

Americans Seek Fresh Start Abroad as Election Sparks Expat Interest

UP NEXT

Trump Promises to Bring Lasting Peace to a Tumultuous Middle East. But Fixing It Won’t Be Easy

What to Know About John Ratcliffe, Trump’s Pick for CIA Director

6 hours ago

Here Are the People Trump Has Picked for Key Positions So Far

6 hours ago

Waymo’s Robotaxis Now Open to Anyone Who Wants a Driverless Ride in Los Angeles

6 hours ago

Fresno County Man Accused of Filing Fake Disability Claims in $300K Fraud Scheme

6 hours ago

Trump Nominates Fox News Host Pete Hegseth for Defense Secretary

6 hours ago

Economists Warn of Inflation and Debt Risks in Trump’s Second Term Plans

6 hours ago

How Many Smoke Shops Is Too Many? Fresno Plan Would Allow Only 49

7 hours ago

US Says It Will Not Limit Israel Arms Transfers After Some Improvements in Flow of Aid to Gaza

7 hours ago

Who With Valley Ties Could Land Spots in the Trump Administration?

8 hours ago

Tulare Gang Member Gets Life Without Parole for 2022 Murders

9 hours ago

Trump Says Musk, Vivek Will Form Outside Group to Advise White House on Government Efficiency

WASHINGTON — President-elect Donald Trump on Tuesday said Elon Musk and former GOP presidential candidate Vivek Ramaswamy will lead a new “D...

5 hours ago

5 hours ago

Trump Says Musk, Vivek Will Form Outside Group to Advise White House on Government Efficiency

5 hours ago

Fate of Clovis Trustee Race Still Up in the Air. So Are Clovis, Sanger School Bond Measures.

5 hours ago

Richardson Widens Lead Over Bonakdar in Nail-Biting Race for Fresno City Council

6 hours ago

What to Know About John Ratcliffe, Trump’s Pick for CIA Director

6 hours ago

Here Are the People Trump Has Picked for Key Positions So Far

6 hours ago

Waymo’s Robotaxis Now Open to Anyone Who Wants a Driverless Ride in Los Angeles

A Fresno County man has been indicted on mail fraud charges for allegedly submitting over $300,000 in falsified disability claims using stolen identities. (GV Wire File)
6 hours ago

Fresno County Man Accused of Filing Fake Disability Claims in $300K Fraud Scheme

Pete Hegseth walks to an elevator for a meeting with President-elect Donald Trump at Trump Tower in New York, Dec. 15, 2016. (AP File)
6 hours ago

Trump Nominates Fox News Host Pete Hegseth for Defense Secretary

Search

Send this to a friend